|
KMID : 0605720130190020101
|
|
Journal of the Korean Society of Biological Therapies in Psychiatry
2013 Volume.19 No. 2 p.101 ~ p.107
|
|
|
Bias and Causal Association in Clinical Research
|
|
Chang Sung-Man
Paik Jong-Woo
Kim Seong-Hwan
|
|
|
Abstract
|
|
|
|
The bias results from the lack of internal validity or incorrect measurement of the association between exposure and effect in the target population. In regard to internal validity, selection bias, information bias, and confounding can appear to some degree in all observational research. Selection bias arises from an absence of comparability among study groups. Information bias is caused by incorrect assessment of exposures, effects, or both. Confounding is a confusing or blurring of effects. Researchers try to relate exposure to outcome but actually measure the effect of a third factor. Confounding can be controlled in several ways - restriction, matching, stratification, and more sophisticated multivariate techniques
|
|
|
KEYWORD
|
|
|
Selection bias, Information bias, Confounding
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|